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Filtered Search Results
Medchemexpress LLC Rentosertib | 2828567-39-9 | 99.96% | 487.57 | 250 MG
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Rentosertib (INS018 055) (compound 112) is an orally active TNIK and MAP4K4 inhibitor with IC50 values of 12-120 nM for both targets. It is for research use only.
- Orally active TNIK and MAP4K4 inhibitor.
- Reduces TGF-β-induced α-SMA protein expression with an IC50 of 27.14 nM in MRC-5 cells.
- Decreases N-cadherin and p-SMAD2/SMAD3 expression, increases E-cadherin expression, and inhibits TGF-β-induced epithelial-to-mesenchymal transition (EMT) and fibroblast-to-myofibroblast transition (FMT) in A549 cells.
- Improves lung function and ameliorates pulmonary fibrosis in Bleomycin-administrated mouse models (3-30 mg/kg, po, twice daily for 2 weeks).
- Reduces lymphocytes in bronchoalveolar lavage fluid (BALF), inhibits pro-inflammatory cytokines, and exhibits anti-inflammatory effects in LPS-induced mouse acute lung injury models (3-30 mg/kg, po, single dose).
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Medchemexpress LLC MEDCHEMEXPRESS LLC
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5000669508 NOTOPTEROL 250MG
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Medchemexpress LLC Benzeneacetic acid, α-hydroxy-, ethyl ester | 774-40-3 | MFCD00004494 | 99.7% | 180.20 g·mol⁻¹ | C10H12O3 | 100 G
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Ethyl mandelate is the ethyl ester of mandelic acid used as an intermediate in pharmaceutical synthesis and organic chemistry. It is supplied with documented purity and batch-specific certificates of analysis and safety data sheets to support quality control and regulatory compliance.
- Ethyl ester of mandelic acid, suitable as a synthetic intermediate.
- Documented purity of 99.73% with certificate of analysis available.
- Provided with batch COA and safety data sheet for traceability.
- Commonly used to prepare chiral building blocks and pharmaceutical intermediates.
- Supplied in laboratory-scale packaging for research and development use.
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Medchemexpress LLC Quinocetone | 81810-66-4 | MFCD09753267 | 98.0% | 306.32 g/mol | C18H14N2O3 | 250MG
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Quinocetone is a synthetic antibacterial compound used as an orally active animal feed additive to improve growth performance and control intestinal infections in livestock and poultry. Supplied for research and analytical purposes, it is provided as a solid or as a DMSO solution and is commonly used in veterinary studies and residue analysis.
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Medchemexpress LLC MEDCHEMEXPRESS LLC
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5000451337 THYMINE STANDARD 250MG
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![eMolecules Synthonix / 6-chloro-2-methylpyrazolo[43-c]pyridine / 50mg / 786490745 / AC79965 / / 1956327-01-7 / MFCD29922264 / 167.600 / C7H6ClN3](https://assets.fishersci.com/TFS-Assets/CCG/product-images/502455002.PNG-250.jpg)
eMolecules Synthonix / 6-chloro-2-methylpyrazolo[43-c]pyridine / 50mg / 786490745 / AC79965 / / 1956327-01-7 / MFCD29922264 / 167.600 / C7H6ClN3
Synthonix / 6-chloro-2-methylpyrazolo[43-c]pyridine / 50mg / 786490745 / AC79965 / / 1956327-01-7 / MFCD29922264 / 167.600 / C7H6ClN3
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eMolecules 4-CHLOROPYRIMIDINE-2-CARBON 1G
5000223738 4-CHLOROPYRIMIDINE-2-CARBON 1G
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eMolecules 4-CHLOROPYRIMIDINE-2-CARBON 5G
5000223736 4-CHLOROPYRIMIDINE-2-CARBON 5G
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eMolecules (2S)-2-AMINO-2-(4-METHOXYPHENYL)ETHAN-1-OL | 191109-48-5 | MFCD09253728 | 1g
AstaTech | (2S)-2-AMINO-2-(4-METHOXYPHENYL)ETHAN-1-OL | 1g | 592487851 | N11095 | 95.000 | 191109-48-5 | MFCD09253728 | 167.208 | C9H13NO2
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Medchemexpress LLC PARP14 inhibitor H10 | 2084811-68-5 | 99.5% | 557.58 g/mol | C24H27N7O7S | 100 MG
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PARP14 inhibitor H10 is a selective small-molecule research compound that targets PARP14 and induces caspase-3/7-mediated apoptosis in cellular assays. It is supplied as a solid and is intended for laboratory research use only.
- Selective PARP14 inhibition with reported IC50 = 490 nM.
- Approximately 24-fold selectivity over PARP1.
- Induces caspase-3/7-mediated apoptosis in cell-based assays.
- High reported purity suitable for research (≈99.5%).
- Molecular weight 557.58 g/mol; formula C24H27N7O7S.
- Soluble in DMSO; supplied in sizes up to 100 mg for experimental use.
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Medchemexpress LLC Pomalidomide 5'-piperazine-4-methylpiperidine (dihydrochloride) | 2758431-93-3 | 98.1% | 512.43 | 250 MG
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Pomalidomide 5'-piperazine-4-methylpiperidine dihydrochloride is a chemical offered by MedChemExpress for laboratory research. This product is stable under recommended storage conditions and is intended for use by qualified scientists in appropriately equipped facilities.
- For laboratory chemical research
- Stable under recommended storage conditions
- Light yellow to brown solid
- Purity of 98.08%
- Recommended storage at 4°C, sealed, away from moisture
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Medchemexpress LLC 3-methyl-5-nitropyridine | 6960-20-9 | MFCD04114214 | 100.0% | 138.13 g/mol | C6H6N2O2 | 10 G
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3-Methyl-5-nitropyridine (CAS 6960-20-9) is an organic intermediate used in the synthesis of pharmaceutical and specialty chemical compounds. Supplied as a powdered reagent, it is intended for research and synthetic applications.
- Chemical intermediate for synthesis of active compounds.
- Molecular formula C6H6N2O2; molecular weight 138.13 g/mol.
- High reported purity (approximately 99.96%).
- Available in multiple pack sizes, including 10 g.
- Powder; store at -20°C (up to 3 years) or 4°C (up to 2 years) as recommended.
- For research use only; not for human or clinical use.
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![Medchemexpress LLC Dibenzo[b,k]hexaoxacyclooctadecin, eicosahydro- | 16069-36-6 | 97.0% | 372.50 | 250 MG](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000451374-logo.png-250.jpg){kind=logo}
Medchemexpress LLC Dibenzo[b,k]hexaoxacyclooctadecin, eicosahydro- | 16069-36-6 | 97.0% | 372.50 | 250 MG
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Dicyclohexano-18-crown-6-ether selectively extracts lysine-rich cytochrome c proteins from other cationic proteins under weakly acidic and neutral conditions, demonstrating specificity in ligand-protein interactions.
- Selectively extracts lysine-rich cytochrome c proteins from other cationic proteins.
- Demonstrates specificity in ligand-protein interactions.
- Shows antiproliferative activity against various cell lines (HeLa, MCF7, MIA PaCa-2, NCI-H460, SW-620).
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Sigma Aldrich Fine Chemicals Biosciences WYE-125132 >=97% (HPLC) | 1144068-46-1 | 25MG
WYE-125132 >=97% (HPLC) | Purity: >=97% (HPLC) | Mol Wt: 519.6 | 1144068-46-1 | 25MG
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Cayman Chemical Fatty Acid ethyl ester Standa
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A pack that contains nine vials EAch containing 100 mg of an individual fatty acid ethyl ester; contains one vial EAch of stearic acid ethyl ester, myristic acid ethyl ester, linoleic acid ethyl ester, α-linolenic acid ethyl ester, arachidonic acid ethyl ester, oleic acid ethyl ester, palmitic acid ethyl ester, lauric acid ethyl ester, or palmitoleic acid ethyl ester
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